It does not look that bad if you look at the path being quoted it is the 5.8.0 path which suggests the perl 5.8.1 executable is running but a path in a configuration file is pointing to 5.8.0 a good search of the config files should find it.
I don't thinki it would be needle in haystack job if they just step through what they are doing and look where everything points. I actually find things like this a great time to read the manual and learn how things are working. Without problems we tend to take these things called computers for granted.
I haven't seen this error before but some google searching with maybe some more system information and an answer should be out there.
Try this link it seems to have some answers:
The FAQ section has some tips for this.