We've got around 200,000 lines of Perl in a system that manages and checks medical laboratory data coming off automated instruments. The usage is 24x7, and people's health depends on the accuracy of the numbers we maintain and verify. The data comes in many different forms, in terms of its inherent structure, as well as how a specific instrument manufacturer has chosen to package it. This makes the agility of Perl a very important feature.
We have another million or so lines of code, mostly in C, that we will be porting to Perl over the next several years.
Hope this helps you in your decisions.
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