The perl web framework Mason seems to play well with Dreamweaver, at least some people manage to get it to play well.
in reply to Dreamweaver/Perl integration tools
If you use the syntax of Mason in Dreamweaver most of the code isn't properly displayed, mainly as simple text. Which is totally uncool for <%INIT> or similar blocks. In a standard DW installation only <% some code %> is displayed as an ASP icon. Specially when you work with graphic designers which are used to WYSIWYG this will help a lot, as HTML looks more like HTML :-) "
The solution... is described at Mason and Dreamweaver
Hope this helps!