If it were me, the first thing I would do is come up with a new glossary for such a "rebel" object, e.g. a "clobe" or "imp" or whatever to avoid confusion with Perl's traditional objects (unless you make your programming users swear allegiance to your cause). An object is usually "new"ed, whereas a "clobe" might be "spun", "baked", "smoked" or whatever you fancy or if "imp" then it might by "incarnated" (so perhaps "incarnation" to replace "instance".
The replacement mechanism for "bless" (..."curse?" ;)) would have to be managed in your own data. But a module-level hash could carry that off. I am not however sure that you can modify a variable in a particular incarnation (closure instance) without having to replace the whole thing and that could be very tricky to code indeed - unless you imposed rules on your imps (or clobes) that would be rather unnatural for closures.