This is probably flame bait, but SQLite is not heavily used (in my experience). It is being used by Mac OS X native applications (e.g. AddressBook etc.). On the other hand, chances are very good that your webserver is running an instance of mysqld and that you can get to a mysql command-line prompt pretty easily. Every single time I've come across a tutorial that used SQLite, I had a hard time getting the correct packages installed, tweaking syntax, etc. I think most corporate/high-traffic applications are going to be using MySQL over SQLite.
But hey, the beautiful thing about the DBI module in Perl is that it makes switching between underlying database engines very easy.
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