The same thing could be said for Java GUI libraries as well. There are a number of issues that every GUI library has and generally there few languages that include a good Visual Design Suite with them(AKA MS Visual Studio).
Personally, when it comes to Perl and GUI's I believe HTML and web browser are better all around. They are more flexible and various libraries are being written that are making them easier to work with(like JQuery). While a browser cannot be used for everything I would say there are a few situations where you need stand-alone application on a desktop.