system("script.sh");
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However I thought that I'd mention a couple of points to go with this.

1. Don't assume that your shell environment variables will be kept - a shell script that works fine on the command line may not work when run from Perl
2. Be careful with your directories - try to make sure you're executing from the right place. It's often worthwhile to do a chdir to the right directory in Perl before calling your script. i.e.  chdir "/path/to/script/";