Well, it annoys me when one insists that another must make a judgement call for one. It's worse than dishonest. It's abdication.
Perl 6 is obviously not ready for what 99% of shops would call production. On the other hand, it's an extremely interesting language that can do a lot already and if I were doing a start-up with at least one really smart hacker, I might just base the code on it at this point to get ahead of the curve. Otherwise, it might be nice to use for internal, non-critical tools just to get the exposure, chops, and start giving feedback, test, and bug reports so it can be ready for prime time sooner.