Interestingly, because Perl 5's mutability under sub declarations was so confusing to people; Perl 6's sub declarations never mutate the grammar. Apart from explicit macros or mixed-in grammar rules, the only thing that can change the grammar is a constant declaration, which declares a word that never takes arguments, much like a 0-ary sub in Perl 5. (Type declarations may be considered a specialized kind of constant declaration, where the constant being declared just happens to be a type.) In Perl 6, there are no barewords, so any unrecognized word is assumed to be a list operator that will be declared later in the same file.
So while Perl 6's grammar is more mutable in theory; it is less frequently mutated by accident.
Another interesting consequence of this decision is that
the blocks supplied to map and grep are not a special syntax, so they require a comma. Likewise use of & in a sub signature does not change parsing. On the other hand, bare blocks are just anonymous closures in Perl 6, so they can be passed in any position, and are not restricted to the first argument as they are with Perl 5's & prototype.