Use Net::SNMP:

#! /usr/bin/perl

use strict;
use warnings;

use Net::SNMP qw(:ALL);

my ($session, $error) = Net::SNMP->session(
    -hostname  => '10.10.10.1',
    -version   => 1,
    -community => 'public',
);

my $result = $session->set_request(
    -varbindlist  => [
        '1.3.6.1.4.1.50000.1.1',  INTEGER, 1,
        '1.3.6.1.4.1.50000.1.2',  INTEGER, 2
    ]
);

$session->close();
[download]

And the 'tcpdump' capture verifies both OID integers set in the same packet.

tcpdump: listening on \Device\NPF_{731EA781-5FB3-4C71-944A-D70C7EE18AA
+7}
15:54:50.646616 c4:17:fe:12:7d:75 > 58:6d:8f:78:ad:40, ethertype IPv4 
+(0x0800),
length 105: (tos 0x0, ttl 128, id 2841, offset 0, flags [none], proto:
+ UDP (17),
 length: 91) 192.168.10.100.52184 > 10.10.10.1.161: [udp sum ok]  { SN
+MPv1 { Set
Request(48) R=1833500672  .1.3.6.1.4.1.50000.1.1=1 .1.3.6.1.4.1.50000.
+1.2=2 } }

  0x0000:  586d 8f78 ad40 c417 fe12 7d75 0800 4500  Xm.x.@....}u..E.
  0x0010:  005b 0b19 0000 8011 5062 c0a8 0a64 0a0a  .[......Pb...d..
  0x0020:  0a01 cbd8 00a1 0047 4b23 303d 0201 0004  .......GK#0=....
  0x0030:  0670 7562 6c69 63a3 3002 046d 4900 0002  .public.0..mI...
  0x0040:  0100 0201 0030 2230 0f06 0a2b 0601 0401  .....0"0...+....
  0x0050:  8386 5001 0102 0101 300f 060a 2b06 0104  ..P.....0...+...
  0x0060:  0183 8650 0102 0201 02                   ...P.....
[download]