I'm not familiar with Server 2008 OR Office 2010...buuut...you might check a couple of things. First, if you installed Office with VBA, check the docs for changes. Running Office from VBA should be almost identical from running it via Perl and OLE, but for some syntax changes. You probably know that a quickstart to automating a task in Office is creating a VBA macro, and then translating it to Perl. Anyway, another possibility is that it's not Word.Application anymore. It's only a shot in the dark, but I hope it helps.
in reply to Re^2: win32::ole and MS Office 2010 over cgi
in thread win32::ole and MS Office 2010 over cgi