http://www.perlmonks.org/?node_id=975036, which does not show a working solution, suggests this can be done by writing and updating a temp file and using a timeout to periodically clear and reload the image from there.
Leaving aside the feeling that a temp file is a kludge, where does this timeout go? In or outside the main loop?
Re^3: gtk2-perl: how to update image widget from callback?
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