|Problems? Is your data what you think it is?|
Filemaker Pro - for interface prototyping, & small business applications in a heterogenous environment.
Also, since I run OS X aka Darwin, yes I use Perl with it.
Also, it functions as it's own web server.
MySQL - backend for serious Perl/Java development and anything that I run personally.
ORACLE - what I reccomend professionally, and get called to work with the most.
ahemINFORMIX - well, I used to build & maintain fully blown Perl applications that would process & deliver 18Gb of financial reports daily... But now they've been bought out by IBM, so who knows, it'll probably fade away.8-P
Wait! This isn't a Parachute, this is a Backpack!