$ perl -E '
> $str = q{G_I1E2_GTGGAG^303CTGgacgCCCTGC_I2E3_TACA};
> say for
> map { tr{[ACGT]}{}cd; $_ }
> split m{[a-z]+}, $str;'
GGTGGAGCTG
CCCTGCTACA
$
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