I would think that would actually increase the number of keystrokes needed by one:

Original Process

Start:
(UP)vim filename.pl(ENTER) (2 keystrokes)
(make changes) (0 keystrokes)
:wq(ENTER) (4 keystrokes) *
(UP)(UP)perl -Wall filename.pl(ENTER) (3 keystrokes)
GOTO Start

Total: 8 keystrokes

Two-Window Process

Start:
(edit .pl file in vim, window1) (0 keystrokes)
:w(ENTER) (3 keystrokes) *
Alt-Tab to window2 (2 keystrokes)
(UP)perl -Wall filename.pl(ENTER) (2 keystrokes)
Alt-Tab back to window1 (2 keystrokes)
GOTO Start

Total: 9 keystrokes

* : only counts as one keystroke because in my .vimrc I have ; mapped to : and vice-versa so I don't need to press the Shift key

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