my %params;
$params{param1}         = $param1;
$params{param2}         = $param2;

 my %options; 
 $options{INCLUDE_PATH} = '/var/www/html/test'; 

 my $msg = MIME::Lite::TT::HTML->new( 
            From        =>  'me@domain.com',
            To          =>  'user@domain.com',
            Subject     =>  "Test",  
            Template    =>  {
                             html    =>  'template.html.tt',
                             text    =>  'template.txt.tt',
                            },
            TmplOptions =>  \%options, 
            TmplParams  =>  \%params, 
            ); 
 # Set our content type properly
 $msg->attr("content-type"  => "multipart/mixed");
 
 $msg->attach(  Type        =>  'application/msexcel',
                Path        =>  '/var/www/cgi-bin/test/test.xls',
                Filename    =>  'test.xls',
                Disposition =>  'attachment'
 ); 

 $msg->send('smtp', 'smtp.domain.com', Timeout=>60);