Overall this group of postings makes a strong case for most Perl users to rely on vendor-provided package management teams and the work they do (especially at Debian). It makes a case for relying on them (and appreciating them), and using what they provide instead of cooking up your own Perl installation.
Not really. The problem in each case is simple %ENV $path management.
What the vendors do is save you precious compilation time, but when they don't provide binaries of a library, you have to compile it yourself