my $twig = XML::Twig->new(
    twig_handlers   => { subfield => \&editHref, },
    pretty_print    => 'indented',
);

$twig->parse($xml);
$twig->print;

sub editHref {
    my ( $twig, $href ) = @_;
    my $text = $href->text();
    my $orig = "(OSt)16";
    $text =~ s/\Q$orig/(OSt)20/;
    $href->set_text($text);
}