yes that is true (why is this so odd ?? in bioinformatics you have 50-500gb read-mapps (files) and nobody finds that odd :) ). Maximum coordinate ?? well that depends on a simulation. but i would say for id = a, max is app. 5*10^9 i mean i need to find this out by going through the file.
Re^2: Counter - number of tags per interval
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One Id app. 8-12 h
50 id's app. 500h = app. 20 days which is 20 times longer then the actual computation since there will be more of such simulations i think a better solution would be preferable. Unfortunately i cannot temper with the simulation part since i have no source , but even if i did i wouldn't do it since there are a lot of heuristics involved which i honestly don't understand.