I'd pick "disease-free" if it were an option. The location (like any real estate) is far more important than the room, as I don't spent much time in the room, and the time I do spend I'm trying to sleep (which depends mostly on the party schedules of other guests). The real primary requirement is walking distance to decent food, coffee and the work itself.
in reply to When travelling, what level of existential comfort do you require?
I'd like to be able to assign to an luser