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SOAP::Lite going to be able to handle this or do I need to use something like LWP?

SOAP::Lite is built on top of LWP, so yes

Does anyone have any examples of code that uses these mechanisms or have any suggestions as the best place to start

use SOAP::Simple and the modules its built upon, they actually generate/validate WSDL

See also: SOAP WSSE site:perlmonks.org; Implementing WS-Security in Perl; SOAP::WSDL::Manual::Cookbook; LWP::Authen::Wsse; Setting XML prefix for tags with SOAP::Lite; https://noisemore.wordpress.com/2009/03/19/perl-soaplite-wsse-web-services-security-soapheader/; Ok I'm stumped. How the heck does LWP::Authen::Wsse work?

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