I'm a developer of some Windows Perl apps on ActivePerl at work, albeit 5.6.1. I've more or less given up on ActiveState's PPM repository, and don't even bother trying to use any PPMs from it. I gather there are other repositories with folks who are more receptive: Randy Kobes' bribes repository and crazyinsomniac's one, but I do my own module installs from CPAN, as I have MVC etc.
I'm also trying out Strawberry Perl at home on my laptop (the only home machine I use Windows on), with a large degree of success! CPAN works out of the box, including C compiles.
Oh Lord, won’t you burn me a Knoppix CD ?
My friends all rate Windows, I must disagree.
Your powers of persuasion will set them all free,
So oh Lord, won’t you burn me a Knoppix CD ?
(Missquoting Janis Joplin)