It's obvious English isn't your first language, so your question is a bit hard to understand, but let me give it a try: You're trying to execute an external application "setup.exe", via the perl builtin
system function, and you want to interact with it?
If thats the case, then it depends on the interface of the setup application...Is it a command line (CLI) or graphic (GUI) interface? If it's CLI, then you can use IPC::Run (or a similar module) to script interactions with it. If it's a GUI, you may be able to use something like Win32::CtrlGUI, though I have no experience with anything like that, so I can't elaborate any further.
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Systems development is like banging your head against a wall...
It's usually very painful, but if you're persistent, you'll get through it.