in reply to
dyld: lazy symbol binding failed (was MAC OS 10.6 upgrade breaks DBD:mysql)
I had to reinstall MySQL when I installed Snow Leopard, but had no problems beyond that.
People starting out on this should make sure that you install XCode from the optional installs, otherwise you'll be missing important things like make and the compiler (obviously you already did this, superdoc).
I downloaded the latest 64 bit MySQL from mysql.com, installed it, started it, and reinstalled DBD::mysql under CPAN and everything then worked.
You'll need to rebuild your actual databases after doing this.