That suggests your machine simply does not have serial ports configured.
To verify, run msinfo32.exe; click Components->Ports->Serial.
In the context of this thread, the usability of Win32::SerialPort under 32 & 64 bit Perls is telling you nothing useful.
With the rise and rise of 'Social' network sites: 'Computers are making people easier to use everyday'
Examine what is said, not who speaks -- Silence betokens consent -- Love the truth but pardon error.
"Science is about questioning the status quo. Questioning authority".
In the absence of evidence, opinion is indistinguishable from prejudice.