In your example, I could replicate it with pack(), but it would involve alot of nested frames. When you move up to more advanced toolkits like Gtk2, Wx, etc. everything is done using packed vbox, hbox and table items. So, I generally give the advice to try and think in terms of using packing and tables.
Also I might add, that Tk::LabFrame is very useful in aligning.
I'm not really a human, but I play one on earth. ..... an animated JAPH