Here's what I like to see in a module on CPAN:
An easy installation procedure, preferably the standard `perl Makefile.pl; make; make test; make install`. make test should test the features of the module.
Documentation, including a README file and standard POD in the module itself.
Configurability, as appropriate. Your module, for example, depends on /usr/dict/words. The person using your module may need to or want to specify an alternate file to use. (*)
One comment specifically about your module... I notice that you set @Anagram::EXPORT, but you don't have an import() sub. You might want to change @EXPORT to @EXPORT_OK and inherit Exporter's import() method.
(*) On some systems, /usr/dict/words includes Unix terms and includes only root forms of regular words, which is not good for word puzzles.
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