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^ in this case is bitwise-OR.

When you bitwise-OR two strings, where the bytes in the two strings are the same, the byte in the resultant string will be chr(0); when they are different, the results will be non-chr(0). This allows you to count the number of differences in two strings very quickly:

$seq1 = 'ACGTACGTACGTACGT';; $seq2 = 'TCGATCGATCGATCGA';; print ( $seq1 ^ $seq2 );; § §§ §§ §§ § print length( $seq1) - ( $seq1 ^ $seq2 ) =~ tr[\0][\0];; 8

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In reply to Re^4: Hamming Distance Between 2 Strings - Fast(est) Way? by BrowserUk
in thread Hamming Distance Between 2 Strings - Fast(est) Way? by monkfan

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