mdi has asked for the wisdom of the Perl Monks concerning the following question:

I need to do multiple substitutions in several large (1-10MB) files. I've been using this:
use strict; use warnings; use Tie::File; foreach my $x (@ARGV) { tie my @f, 'Tie::File', $x or die "Could not tie $x: $!\n"; for (@f) { s/^\|/\\N\|/; s/\|\s*$/\|\\N/; s/\|\s*\|/\|\\N\|/g; s/\|\.\s*\|/\|\\N\|/g; s/\|\s+/\|/g; s/\s+\|/\|/g; s/(\d{2}:\d{2}:\d{2})\.\d+/$1/g; s/(\d{5})-(?:\d{1,4}|\s+)/$1/; } }
...but this is taking entirely too long, and using up too much CPU. How can I do this more efficiently?