Re: Cleaning up a text file with compact regex

[Samy_rio]

Try like this,

TIMTOWDI

use strict;
use warnings;
my @content = <DATA>;

@content = grep!/^\;/, @content;
print @content[6..$#content];
__DATA__
<h3>Warning</h3><blockquote><FONT SIZE=+1 color=#aa0000><B>
Circular contig    NC_001224.1    leftmost feature    0    Q0050    le
+ft neighbour    Q0275
</B></FONT></blockquote><BR><HR SIZE=3>
<h3>Warning</h3><blockquote><FONT SIZE=+1 color=#aa0000><B>
Circular contig    NC_001224.1    rightmost feature    18    Q0275    
+right neighbour    Q0045
</B></FONT></blockquote><BR><HR SIZE=3>
>YJR152W|DAL5
TGATTTTGGATATTCATCAAAGGAAACCCTATTAATGGGTTTACCTACAGGTGCTGTTGA
ATTGGTAGGTTGTCCACTTTTTGGTATTCTAGCAGTTTATGCAGCCAATAAGAAGATACC
ATTTTGGAAATATAAGTTGAGTTGGGCTATTTTTGCAGCTGTCTTAGCATTGATTGCTAG
CTGCATGTTAGGGTTTGCAACAAACTCCAAAAAAGCAAGACTGGCTGGTGCTTACCTGTG
GTACATCTCGCCCGTCTCATTTATTTGCGTACTTTCCAATATCAGTGCGAATTCCTCGGG
ATATAGTAAAAAATGGACTGTATCTTCAATAAACTTAGTAGCATATGCTGCAGCTAACTT
GGCAGGACCACAAACCTTTATTGCTAAGCAGGCTCCTAAATATCATGGCGCTAAGGTCGC
TATGGTCGTATGTTATGCTGTTATGATCGTGCTTCTATCTATACTGCTCATCGTCAATTT
AAGGGAAAACAAGAGACGTGATAAGATAGCTGCCGAGAGAGGGTTCCCTGAAGAAACAGA
GAATTTAGAGTTTTCTGATTTGACTGATTTTGAAAATCCAAATTTCAGATACACTTTATG
>YKR039W|GAP1
CCTAGCTGAACAGAGATTTCTGCCAGAAATCTTTTCCTACGTTGACCGTAAGGGTAGACC
ATTGGTGGGAATTGCTGTCACATCTGCATTCGGTCTTATTGCGTTTGTTGCCGCCTCCAA
AAAGGAAGGTGAAGTTTTCAACTGGTTACTAGCCTTGTCTGGGTTGTCATCTCTATTCAC
ATGGGGTGGTATCTGTATTTGTCACATTCGTTTCAGAAAGGCATTGGCCGCCCAAGGAAG
AGGCTTGGATGAATTGTCTTTCAAGTCTCCTACCGGTGTTTGGGGTTCCTACTGGGGGTT
ATTTATGGTTATTATTATGTTCATTGCCCAATTCTACGTTGCTGTATTCCCCGTGGGAGA
TTCTCCAAGTGCGGAAGGTTTCTTCGAAGCTTATCTATCCTTCCCACTTGTTATGGTTAT
GTACATCGGACACAAGATCTATAAGAGGAATTGGAAGCTTTTCATCCCAGCAGAAAAGAT
GGACATTGATACGGGTAGAAGAGAAGTCGATTTAGATTTGTTGAAACAAGAAATTGCAGA
AGAAAAGGCAATTATGGCCACAAAGCCAAGATGGTATAGAATCTGGAATTTCTGGTGTTA
;WARNING    invalid query foo
;WARNING    invalid query bar
;WARNING    invalid query qux

[chromatic]

Just a note:

my @content = <DATA>;

Slurping genomic data into memory may be expensive in time and resources. In this case it may not be an issue, but data sets run large in bioinformatics, so line or chunk processing is often much more feasible.