I did use PPM a while back when I did primarily win32 programming. But I've never used ActiveState's perl distro on Linux. Even on windows I've started using Strawberry Perl, as it comes with useful GNU toolchain for building XS modules
I have used other AS programs in the past on Linux without isuue, like Komodo and KomodoEdit.
On Ubuntu almost everything you'll need is available via apt-get, and for everything else there's CPAN.