Next time you talk to db-guy, you can point out bioperl. It is an open-source tool for bioinformatics and the source of many questions on PM. It leverages exactly Perl's strengths for processing genetic information - strings of [ATGC].
On a more abstract level, I'm curious how you are defining "science", since almost all the apps I know in science are written in either Fortran or C. If you are doing any kind of serious numerical computation, you would be hard pressed to get the kind of speed you can get out of well-optimized Fortran code, plus there's the legacy effect. I personally am trying to leverage Perl's and Fortran's strengths (they are very complementary) toward my own work, though $work is getting in the way there.
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