#!/usr/bin/perl

use warnings;
use strict;

open( OUTPUT, ">output" ) or die "Unable to open output\n$!\n";

$,=","; $\="\n";
while (<DATA>) {
 print OUTPUT map { $_ =~ s/\D//g; $_ } split(':',(split(' ',$_))[-1]);
}

close OUTPUT or die "Close output failed\n$!\n";

__DATA__
3434 34456 7788 9999 65444 4 444 444 44443225 12ms:233ms:455ms
755655 5789 333 666776 5553 353534 33 321ms:543ms:45ms