Be that as it may, I usually use OLE to do this sort of thing, and I often wind up doing it in Excel. In other words, and if the spreadsheet is important and fixed, instead of writing an external script to read the Excel data, I write a VB script within Excel to push the data out. I write the script to use named cell ranges, rather than coordinates.
Now, the “export such-and-such range of data” capabilities within Excel are already very powerful, and this is a very common task. Explore all of your alternatives carefully.