One target audience for PFWSM is web monkeys who use O'Reilly books, but don't know how to program. They want to learn Perl/CGI/"automate my website", so they check out the O'Reilly titles.
That's what I did. I tried to teach myself Perl with the Llama, but I don't know how to program. (I've picked up much of my 'knowledge' about programing from Slashdot, so I'm trying to learn good habits from here and O'Reilly.) The Llama without a programming background is hard: I got through most of it, but still wasn't comfortable with what I 'knew'. (Plus I was finishing my senior design project in college. :) With PFWSM, I'm comfortable with features as I learn them. Additionally, much of my motivation for learning Perl & programming is automating web sites & automating local tasks.